Cannabis Research: Alzheimer’s Disease
Alzheimer’s is a physical disease of the brain and one of the most common causes of dementia. It causes the formation of “extracellular” and “fibrillar” deposits, which means that cells die in the brain. This progressive disorder causes slowly more and more brain damage, in which the mental condition of the patient gradually deteriorated. The symptoms of Alzheimer’s disease are:
Memory Loss – Is easily confused and finds it difficult to remember names, places, people and recent events.
Mood swings – Can easily be angry, anxious or frustrated as a result of increasing memory loss.
Withdrawal – Pulls emotionally still further back, the more difficult the communication.
Cannabis & Alzheimer’s studies:
1) prevention of Alzheimer’s disease pathology by cannabinoids: neuroprotection by blockade of microglial activation (Prevention of Alzheimer’s Disease Pathology by Cannabinoids: Neuroprotection Mediated by Blockade of Microglial Activation – 2005)
Cannabinoids are known to act as neuroprotective agents in the brain. This prompted the researchers, the function of the cannabinoid receptors and the possible protective properties that have the cannabinoids in marijuana to judge in Alzheimer’s patients. They found that the cannabinoid receptors play a role in the illness and that prevent the cannabinoids that the neurodegenerative process is taking place. Published in the “Journal of Neuroscience.”
2) Marijuana slows decay by Alzheimer’s disease (Marijuana Slows Alzheimer’s Decline – 2005)
Studies of the Hebrew University in Jerusalem, who were eye aimed to find out whether the non-psychedelic cannabinoids in cannabis may help in the treatment of Alzheimer’s disease. They found positive results in mice, which indicated that the use of cannabis could slow down the degeneration of memory. Published by the “Israel National News”.
3) A molecular link between the active component of marijuana and Alzheimer’s disease pathology (A Molecular Link Between The Active Component of Marijuana and Alzheimer’s Disease Pathology – 2006)
This research aimed to find out what role THC, in contrast to the non-psychoactive cannabinoids, could play in the treatment of Alzheimer’s disease. It has been found that THC inhibits effectively the AB Group, the principal pathological markers of Alzheimer’s disease. They took together that the effect that had THC, was even better than that of prescription drugs that were at the time available. Published in “Molecular Pharmaceuticals.”