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cannabis helps in the reduction of pain associated with rheumatoid arthritis Posted on 07 Jun 09:31

 

A drug that has been obtained from Cannabis extracts helps in the reduction of pain associated with rheumatoid arthritis. However, those who believed that the patient now smoke joints, is wrong.
The medicine (Sativex) was developed by the British company GW Pharmaceuticals, which has a license from the government to research the benefits of cannabis. Tests with a spray version of the preparation at 58 arthritis patients showed that it reduces pain and improves sleep quality. Few patients developed side effects.

Philip Robson, director of the research department: "These results are really exciting because this is the first controlled clinical trial of a cannabis-based drug is for the treatment of arthritis”. The study is now focused on the optimal treatment dose.

The Arthritis Research Campaign has welcomed the study. A spokeswoman said: "It will not cure the disease, but it will do a lot to manage pain and suffering of people with rheumatoid arthritis." Furthermore , cannabis is less likely to be harmful than other painkillers. The idea that people with rheumatoid arthritis smoking joints and getting high, is wrong. Painkillers that are based on cannabis, should be taken seriously.

Previously, scientists commissioned by the Arthritis Research Campaign conducted studies which showed that cannabidiol, a natural component of cannabis, which in its processed form has no psyche-changing effect, can ease the effects of collagen-induced arthritis in mice.

WANC 18:06:04 / pte


Study: Cannabidiol (CBD) may help treat social anxiety disorder Posted on 07 Jun 09:25

Study: Cannabidiol (CBD) may help treat social anxiety disorder
Date: 04.19.2015

The relationship between cannabis and anxiety is very interesting. Large detetrahidrocannabinol concentrations (THC) is often associated episodes of paranoia and anxiety, but is well documented that cannabidiol (CBD) in cannabis may counteract this effect.
, an article published in the Journal of Psychopharmacology 2011 by a group of Brazilian researchers examined the relationship between cannabidiol (CBD) and social anxiety disorder (SAD). Their results suggest that CBD could be a way for people who suffer from SAD to help, offer to manage your symptoms.
What is Social Anxiety Disorder (SAD)?
What is the impact on 12% of Americans in his life, social anxiety disorder (SAD) is the most common form of anxiety and one of the psychiatric disorders in general. It is also called social phobia.
By definition of social anxiety disorder is characterized by an intense fear in one or more social situations. In turn, this fear may distress to the point, cause impaired daily functioning.
Brazilian researchers are investigating CBD, fear in the people. To understand the relationship between cannabidiol (CBD) and anxiety test, the research team from Brazil recruited 10 individuals with a diagnosis of social anxiety disorder (SAD). We then functional imaging to measure the amount of blood flow to various parts of the brain, having regard to the effects of CBD.
At the first meeting half an oral dose of 400 mg cannabidiol (CBD) and the other half were treated with placebos received. in the second session these roles were reversed, so that all 10 particpants were treated with CBD at any given time. "These results suggest that CBD reduces anxiety in SAD and that this paralimbic related to its effects on activity in limbic areas in the brain” - Dr. JA Crippa
According to the results of the study was associated opinion cannabidiol (CBD) with a significant decrease in anxiety. Cerebral blood flow after treatment CBD also seems to an anxiolytic (anti-anxiety) in areas of the brain, the emotions refer to control. Extension, what does all this mean, Dr. JA Crippa, head of the research team in Brazil. "These results suggest that CBD reduces anxiety in SAD and that this on its effects on activity in limbic brain areas and related paralimbic" says Crippa.


Anti-cancer drugs in leukemia Posted on 07 Jun 09:20

Science / cells: basic research shows that non-psychotropic cannabinoids cannabidiol are effective as anti-cancer drugs in leukemia

New research has shown that no psychotropic cannabinoids of the cannabis plant could be effective anti-cancer drugs. The anti-cancer properties of THC, the primary psychoactive component of cannabis, are recognized for many years. The study was conducted by the team at the St. George's University in London with leukemia cells. The team of Dr. Wai Liu and his colleagues conducted laboratory tests with a number of cannabinoids, either alone or in combination with the other. Of the studied cannabinoids exhibited any such strong anti-cancer properties as THC. Remarkably, they showed when combined together an increased effect on the cancer cells,.

Dr. Liu said: "These substances are able to affect the development of cancer cells to stop them on their way and prevent them from growing. they can destroy cancer cells In some cases, through the use of specific dosage pattern. In combination with available treatment methods we could discover some highly effective strategies for cancer therapy. "The study examined cannabidiol (CBD), cannabigerol (CBG) and Cannabigevarin (CBGV).

Press release of the St George's University of London. October 14, 2013


Hemp and Medicine Posted on 23 Mar 10:53

 

Cannabidiol (CBD)

Cannabidiol (CBD) may be regarded as the counterpart of tetrahydrocannabinol (THC), since it suppresses the effect. It affects, among others, analgesic, anxiolytic, calming slightly, intraocular pressure-lowering, anti-epileptic and antibiotic.

 

Hemp and Medicine

In today's medicine, there would be a number of uses for cannabis products. Unfortunately, the intake of natural cannabis products for medical purposes in Central Europe with the exception of Holland is still not legal. Instead, at great expense synthetic cannabinoid compounds, such as dronabinol produced, which can be prescribed under strict medical supervision.

However, many patients believe that smoked cannabis looks much better than the synthetic or semi-synthetic preparations. This is probably due to the unique combination of active ingredients of the cannabis plant, which lacks the synthetic preparations containing only THC. In particular the absence of cannabidiol (CBD) is likely to be detrimental.

Another problem is that many doctors are still a negative attitude about cannabis, or not yet know about the medical benefits of cannabinoids know.


Sativex ® spray approved cannabis extract Posted on 23 Mar 10:50

Sativex ® spray approved cannabis extract against spasticity in multiple sclerosis in Switzerland

Wednesday, January 29th, 2014
The Sativex spray with cannabis extract for use in the oral cavity is already in several European countries in trade (for example, in Germany and the UK). In Switzerland and in France the drug recently got regulatory approval, but is not currently in distribution.
Included in the Sativex spray is a thick extract of cannabis flowers and cannabis leaves.

This extract is composed of equal parts of the phytocannabinoids tetrahydrocannabinol (THC) and cannabidiol (CBD). The two active ingredients affect the endocannabinoid system, which is involved in the regulation of neuronal and neuromuscular signal transmission.

In multiple sclerosis patients, this system is severely compromised, as it comes as a result of neurodegeneration in a reduction of endogenous cannabinoids.

In the Sativex spray the psychoactive effects of THC by the antipsychotic CBD is überwiegendst prevented.

The indication of the Sativex spray is very limited: Sativex is used for symptom improvement in patients with moderate to severe spasticity due to multiple sclerosis, when the symptoms can not be adequately relieved by other anti-spastic drug therapy. In addition, an initial therapeutic trial must have produced clinically significant improvement in spasticity associated with the symptoms.

It is a titration of up to two weeks is required to achieve the optimum dose.

The patient may gradually by a puff of spray per day increase the dose up to a maximum of 12 sprays daily until optimal relief of symptoms occurs. Distances of at least 15 minutes should elapse between the bursts. The Sativex spray is administered under the tongue or on the inside of the cheek


CBD High therapeutic potential Posted on 23 Mar 10:48

CBD High therapeutic potential

 

Recently, the American television station CNN has reported a lurid story about the fate of the seven-year-old Charlotte from the state of Colorado. She suffers from a whole rare but cruel form of epilepsy, the Dravet syndrome. The disease begins in the first months of life and is associated with partially over a hundred seizures a day, which are hardly treatable. The disease prevents normal development, a mental disability is the result. Meanwhile, Charlotte has the ability to walk, talk and eat almost entirely lost. Conventional medicine was at her wit's end. They even considered to put the child in an induced coma to allow his body a rest.
The father, meanwhile, sought diligently for a therapy that promises relief from his child - until he came across cannabis. After he had heard that a boy with Dravet syndrome in California was successfully treated with it, he wanted this must have therapy for Charlotte. The effect was striking: the spasms died within hours after.

High therapeutic potential

Rudolf cautery, pharmacist and specialist for cannabis at the University of Bern, reporting on CNN followed closely. About the amazing effect he was less surprised. Since he started in the mid 1990s as a Swiss pioneer of the cannabis research, he was able to observe such effects again. Exciting, however, he found the fact that with such contributions cannabis'm getting acceptable and had been pre-CBD, a constituent of the hemp plant without a"High" effect.

For a long time the research according to cautery has previously focused on THC. However, its application is a problem because of the intoxicating effect. While CBD, as recently discovered, neutralizes this effect, or at least reduced and in addition has a cancer and anti-inflammatory effect. Been known for is its anticonvulsant, anxiolytic, and nausea-relieving effect. "In addition, it has a low toxicity and few side effects," says the pharmacist.


Cannabinoids research Posted on 23 Mar 10:46

Momentum in research

THC and CBD are among the 66 cannabinoids to the most promising therapeutic agents. Cannabinoids have been used primarily to treat neurological disorders such as multiple sclerosis or epilepsy, against the side effects of chemotherapy or for chronic pain. The discovery of the CBD and its potency was loud cautery of cannabis research a new impetus. So cannabis is always open for the natural remedy new research approaches, such as use in breast cancer, or psychosis.

New impetus is also on the Swiss cannabis "Market": The revision of the Narcotics Act two years ago, the Federal Office of Public Health may recently also grant exemptions from natural cannabis, so far this only synthetic THC was reserved for the loud professionals, however, far less effective is.

This legal niche allows the use of Medizinalcannabis, although cultivation and consumption of THC-containing cannabis, as in most countries is still prohibited. However, even minor, international pharmaceutical companies to mix with this increasingly lucrative market. So soon comes "Sativex" on the Swiss market, inhalation spray on the basis of THC and CBD in the treatment of muscle spasms in multiple sclerosis. The same company has received these days in the U.S., the approval of clinical trials in epilepsy patients with a CBD-containing spray.


CBD, THC and CBG – A closer look at the cannabinoids Posted on 23 Mar 10:43

CBD, THC and CBG - A closer look at the cannabinoids

 

Cannabinoids

Cannabis contains over 480 active ingredients, of which 80 have been found only in cannabis. That's a lot of different variables that affect the body and that's partly the reason why there are always new published scientific research describing new discoveries around cannabis. The compounds 80, which are only found in cannabis are termed cannabinoids. These interact with the receptors in our body, they trigger reactions in our nervous system and brain. Here below is a brief overview of the 8 main cannabinoids found in marijuana.

THC

Tetrahydrocannabinol This is the best known and most abundant cannabinoid in Cannabis, it stands for Δ-9-tetrahydrocannibinol. This cannabinoid is responsible for the main psychoactive effect, which can be experienced in the consumption of cannabis, it stimulates areas of the brain, which causes the release of dopamine - which in turn causes a feeling of euphoria and well-being. THC also has an analgesic effect, it relieves the symptoms of pain and inflammation. Combined, this causes a great feeling of relaxation.

CBD

CBD Cannabidiol or CBD abbreviated is, tends to be in terms of quantity the second most abundant cannabinoid in marijuana. It hasa serious impact on the medical field and is the most desirable combination of medical users. It is a non-psychoactive component, probably reduces the effects of THC and regulated. This means that varieties with a lot of CBD next to the THC trigger a frenzy, in which the head is much clearer than eg in the Haze varieties that contain very little CBD. CBD itself has a long list of medical properties. Among the most important things here are the relief of chronic pain, inflammation, migraine, arthritis, cramps and epilepsy and schizophrenia. CBD has also shown properties that act against cancer and with each new benefit further research are constantly being found.

CBN

Cannabinol Cannabinol or CBN abbreviated, is an analgesic that ensteht by the degradation of THC by oxidation. It is easy psychoactive and can be found in fresh cannabis plants only in small amounts. Its occurrence can be reduced to a minimum by storing harvested cannabis in a dark, dry place. Tends to the effect of THC the preferred CBN, for CBN is not as effective as THC and may cause fatigue, if it occurs in high concentrations. From it is also known that it reduces anxiety and reduces the intraocular pressure.

 

CBG

Cannabigerol CBG, also known as cannabigerol, is an active ingredient in cannabis, which is known for its antibacterial effect. It was noted in recent research that there are varieties Although traditionally not very common in most cannabis, but that it probably is the "template" or "stem cell" for both THC and CBD. This means that THC and CBD emerge from the CBG. CBG was also found to inhibit the uptake of GABA, resulting in a feeling of relaxation, which is normally associated with the CBD. These findings have spurred new research in this cannabinoid, which could come out that it might also have a greater impact.

THCV

THCV Of tetrahydrocannabivarin THCV or abbreviated, it is believed that it is a cannabinoid that attenuates the intensity of the psychoactive effects of THC. Current research is carried out to THCV, suggests that it can be used to treat metabolic disorders and functions as an appetite suppressant.

CBC

Cannabichromene Although not much medical research has been performed in this cannabinoid suspected of cannabichromene or abbreviated CBC, it has anti-inflammatory and analgesic effects. Let recent research suggests that it potentially plays a role in cell regeneration in the brain.

 

THCA

Tetrahydrocannabinolicacid THCA is an acid form of THC. It is a raw state in which THC in fresh cannabis plants can be found. Only when cannabis is heated, the THCA is converted to THC. THCA from this raw form, it is believed that there is no active connection.

CBDA

  Similar to THCA, CBDA is the acid form of the CBD. It is currently believed that it has an antiemetic effect (anti-nausea effect), and that it helps to combat breast cancer.However, more research on its medicinal benefits of distress.


The endocannabinoid system Posted on 23 Mar 10:35

The endocannabinoid system

It is likely that you have encountered while reading the comments on cannabis, as the cannabinoids with receptors in our body interact, without really knowing what is to be understood. Well, no more question you, here is our short guide when it comes to this matter.
The network of receptors in our body, also known as the endogenous cannabinoid system is the part that is responsible for maintaining the overall health and it is probably one of the most important physiological systems in our body. This system, which was, after cannabis, the plant, which led to its discovery, named, extending through the whole body. It fulfills a variety of functions, but its main purpose is the maintenance of homeostasis - the regulation and maintenance of a stable environment within the human body.

CANNABIS AND THE ENDOCANNABINOID SYSTEM

Human Nervous System The similarity between the names is the first thing that catches an eye. The reason is that the cannabinoids contained in cannabis, which are extremely similar to that produced naturally by our body - the endocannabinoids. "Endo" is the short form for endogenously, which comes from the Greek "generated inside" produced by the body itself. Outside of a living organism 'cannabinoids found in cannabis only, hence the name.
It was the particular way interact as cannabinoids from the cannabis with our system, which led to the realization that we have our own natural form of cannabinoids. If our bodies are fed cannabinoids, this causes an interaction with the endocannabinoid system, which is why we experience the physiological and psychoactive effects of marijuana. A very simple way of looking at is this: The body produces endocannabinoids to regulate its own system and to modulate and if we bring the cannabinoids from the cannabis, we turn the system into overdrive, as we increase the amount of available cannabinoids.

 

CB1 AND CB2 RECEPTORS

Receptor The endocannabinoid system consists of various receptors, all of which interact in different ways with the cannabinoids and lead to different results, but all with the same goal in mind - homeostasis. The two most important receptors within this system are known as CB1 and CB2 receptors. CB1 receptors are mainly located in the brain and nervous system, whereas CB2 receptors are part of our immune system. It is the way in which the various cannabinoids in marijuana bind to these receptors and interact with them, which trigger the holistic and profound effects, which we can then feel. It is interacting with our body system because of the manner in which THC, CBD and the many other lesser known cannabinoids - very often to our advantage. That is the reason why cannabis has such far-reaching impact on medical science.

THE EFFECT

What all this shows is that cannabis grows not only on this planet to make us "high" (although many love to be just that). Amazingly, research has shown that cannabis plants use the cannabinoids in their systems in order to obtain their own healthy growth and promote. It seems that the cannabinoids have a similar function for us, as for the cannabis itself supported by long historical use, a large area of scientific research seems the medical potential of cannabis in a variety of diseases, such as epilepsy, diabetes, and arthritis affirm. It is also used to alleviate pain and reduce inflammation.
But for slander politicians and greedy companies who use cannabis have pushed a bad reputation, much needed research was suppressed. Fortunately, this negative attitude with more and more sound, scientific researches that investigate the properties of cannabinoids and what benefits they have for the body, then slowly broken down. As a result, begin now to many countries, including the U.S., as the marijuana to see what it really is. recent research has shown that cannabinoids can act as a preventive agent to treat cancer, and may help repair brain damage caused by alcohol? And that is only scratching the surface, because scientists are constantly finding new uses and effects - we should be prepared for a pretty exciting time!


Sativa compared to Indica: Medical effects Posted on 23 Mar 10:32

Sativa compared to Indica: Medical effects

Sativa and Indica are two different species of the cannabis family. They show various properties of cultivation, cause different noise conditions and have different medical effects. An understanding of the differences can be used for medical users make the difference when choosing a variety.

SATIVA COMPARED TO INDICA: MEDICINAL PROPERTIES

Sativa and Indica are two different species of the cannabis family. They show various properties of cultivation, cause different noise conditions and have different medical effects. An understanding of the differences can be used for medical users make the difference when choosing a variety.
SATIVA COMPARED TO INDICA: MEDICINAL PROPERTIES
On the chemical level Indica and Sativa varieties differ in their composition of the cannabinoid content, as well as in that of the other phytochemical compounds such as terpenes and flavonoids. Sativa varieties usually show a high THC content and a low CBD content, while pure Indica varieties usually have a lower THC content and a slightly higher CBD content. But thanks to the breeding, both Indica and Sativa varieties with different THC can: CBD concentrations are found.
In general, the effect of Sativa varieties often is described as a strong and uplifting, cerebral intoxication (high), while Indicas tend to be a body-related, numbing (stoned) elicit action. While the THC and CBD play a significant role in shaping the action, other naturally occurring substances play their part in creating these different properties. For example, more than 120 different terpenes were found in cannabis, can greatly affect their concentration and ratio of the noise, the one sort of causes.
After THC CBD is the second most common and most important cannabinoid that occurs naturally in Cannabis; and it is not only believed to be medically useful, but it changed the manner as THC interacts with the body, whereby the action of THC modulated and attenuated. Generally speaking, based on the natural variation in plant chemistry, the rule of thumb that works on the mind and Sativa Indica on the body.

Medicinal properties of Sativa:
Stimulating & uplifting
Stimulates creativity and thoughts
Promotes the well-being
Relieves headaches and migraines
Reduces nausea
Stimulates the appetite
Relieves depression
Medicinal properties of Indica:
Relaxing & easy making
Relieves pain and joint Pull
Reduces anxiety and stress
Promotes Sleep
Reduces inflammation
Helps to relieve spasms and seizures
Stimulates the appetite

Hybrid varieties are a combination of Sativa and Indica varieties and were bred to combine properties. There is no universal list of the medicinal properties of cannabis hybridized varieties, as they were bred literally to include a wide range of effects that differ from variety to variety. In general, most medical However, users are looking for the kind that brings them the most benefit, a CBD-rich, dominated by Indica or Sativa variety.

SATIVA COMPARED TO INDICA - THE DIFFERENCE IN GROWTH

SATIVA COMPARED TO INDICA - THE DIFFERENCE IN GROWTH
While the medical user is primarily interested in the medicinal effects, some may know about their properties during growth, help in the practical side of things.
Growth characteristics of Sativa
Sativa varieties tend to grow in height, often towering somewhere between 1-3 meters and sometimes up to 5m when they grow outdoors. Sativa varieties are long and thin as a rule, but can also be quite bushy when they grow untrimmed. Because of the longer flowering period they are well suited for growing outdoors.

                             Sativa

 

                                      Indica

Growth features of the indica

Cannabis Indica varieties are shorter and of buschigerem growth generally. Its leaves are thick and dark green color, which is due to the higher amount of chlorophyll. Indicas produce heavy buds and fragrant, with a yield which is usually higher than that of a Sativa. They also have a shorter flowering period than sativas, which is why they are preferred for growing indoors.